Germs

A new compound called CMX410 may change the fight against tuberculosis. It targets a weak point in the bacteria’s defenses, even in drug-resistant forms of the disease. Created using a cutting-edge chemistry method, the drug shows promise for being both powerful and safe. Scientists believe it could lead to shorter, more effective treatments for millions of people. Read more »

Walking a few thousand steps daily may help hold off Alzheimer’s for years, a Mass General Brigham study found. Even moderate physical activity slowed both cognitive decline and the buildup of harmful tau proteins in the brain. The researchers say these results show lifestyle changes can meaningfully delay Alzheimer’s symptoms, especially in early stages. Read more »

A collaboration between Brazilian and German researchers has led to a sunflower-based meat substitute that’s high in protein and minerals. The new ingredient, made from refined sunflower flour, delivers excellent nutritional value and a mild flavor. Tests showed strong texture and healthy fat content, suggesting great potential for use in the growing plant-based food sector. Read more »

Researchers at MIT’s Picower Institute found that rotating waves of brain activity help restore focus after distractions. In animal tests, these rotations predicted performance: full rotations meant full recovery, while incomplete ones led to errors. The brain needed time to complete the cycle, revealing a biological rhythm of cognitive recovery. Read more »

Researchers have discovered a specific set of neurons in the amygdala that can trigger anxiety and social deficits when overactive. By restoring the excitability balance in this brain region, they successfully reversed these symptoms in mice. The results point toward targeted neural therapies for emotional disorders. This finding could reshape how anxiety and depression are treated at the circuit level. Read more »

Using powerful 7-Tesla brain imaging, researchers mapped how the brainstem manages pain differently across the body. They discovered that distinct regions activate for facial versus limb pain, showing the brain’s built-in precision pain control system. The findings could lead to targeted, non-opioid treatments that use cannabinoid mechanisms instead of opioids, offering safer pain relief options. Read more »

Long-term melatonin use for sleep problems may come with unexpected heart dangers. Researchers found that chronic users were almost twice as likely to die and 3.5 times more likely to be hospitalized for heart failure. Though melatonin is widely regarded as harmless, experts now urge caution with extended use. Read more »

Researchers at McMaster University have discovered that the eyes may offer a powerful, non-invasive way to assess heart health and biological aging. By analyzing retinal scans alongside genetic and blood data from over 74,000 participants, they found that simpler, less branched eye vessels were linked to higher cardiovascular risk and faster aging. Read more »

Researchers found that embodying a digital, childlike version of one’s own face helps unlock vivid childhood memories. This illusion strengthens the connection between bodily self-perception and autobiographical recall. The findings suggest that memory retrieval is not purely mental but deeply linked to how we perceive our own bodies. Such insights could lead to tools for recovering forgotten memories or treating memory loss. Read more »

UC San Diego researchers combined artificial intelligence with molecular biology to unravel how immune cells in the gut decide between inflammation and healing, a process gone awry in Crohn’s disease. They discovered that the NOD2 gene’s interaction with a protein called girdin is crucial for maintaining balance. When this connection is lost due to a common mutation, inflammation spirals out of control. Read more »